Donna Ryan, MD, Professor at Louisiana State University’s Pennington Bio-medical Center says “ The Pharmacotherapy will provide a guideline that acts as a roadmap to the clinicians or doctors considering some anti-obesity drug treatment for patients to those who are not finding any success just by doing exercise or going on with simple diets.” She also added that “ This new guideline provides doctors with recommended medications that are clinically proven and also with the provided dosage based on the obesity-related problems and that too including type 2 diabetes and cardiovascular (heart) disease. Further, it also provides some specific recommendations to the patients regarding the cause of their weight gain and any shifted treatment that they are taking and in treating the weight first and foremost properly.”
The Endocrine Society also made some recommendations and highlighted them from the guidelines, it includes the implications for continuing and discontinuing a medicine, providing guidance to prescribe medications that would take effect in reducing the weight or would have no effect on weight, and disclosure of details about the recommended medication-related weight gain or loss to patients to promote shared decision making.
The Endocrine Society has issued a Clinical Practice Guideline (CPG) on Jan 16, 2015, which includes the strategies for prescribing drugs that help to manage obesity and to promote weight loss. The CPG has entitled it as “ Pharmacological Management of Obesity: An Endocrine Society Clinical Practice Guideline,” that was published online and has appeared in February 2015 edition on the Journal of Clinical Endocrinology and Metabolism (JCEM), it is a publication belongs to the Endocrine Society.
Obesity is really a raising problem which affects a person’s health both physically and mentally. According to the survey taken by the National Health and Nutrition Examination Survey on 2012, about 33.9 percent of adults of ages between 19-79 were overweight and 13.4 percent of them were obese and 6.4 percent of them were extremely obese.
Phentermine is one of the anti-obesity drugs that has been approved by the Food and Drug Administration along with three other drugs of the same name, Lorcaserin, Bupropion and Liraglutide in the past five years. These are the appetite suppressants and can be used in combination with your usual diet and exercises which helps in losing weight gradually.
Caroline M. Apovian, MD, of Boston University School of Medicine and Boston Medical Center, said: “ Changing the Lifestyle will always be the central part of any weight loss strategy, it is always the best part in losing a weight.” Caroline also holds the Chair of the task force that authored the guideline. She also added the fact that “Medications that we procure do not act themselves unless we put some efforts in such as maintaining a healthy diet by keep reducing the appetite. Adding medication to our accordingly to our lifestyle changes will also result in some greater weight loss.”
In the Clinical Practice Guideline (CPG), the Endocrine Society recommends that it is must to include a perfect follow up of diet, regular exercise and other behavioral modifications to be a part of all obesity management if a person is intended to lose weight. Other than using Phentermine, an appetite suppressant, a person can also have Bariatric surgery which includes in a behavioral change as it helps in reducing the intake of food and also increases the physical activity such as regular exercise. Some patients might be unable to lose their weight and to maintain the goal weight may be the users of prescription drugs if they follow the drug’s label.
If a patient’s response is well, positive, and has resulted in 5 percent of more weight loss in three months, then the medication can be continued for an extended period. If the patient is unresponsive to the weight loss drug, as they experience any side effects, then it is just to stop the prescription immediately and must have to seek a medical assistance.
Some patients have associated with weight gain, and when they have been prescribed with the drugs for treating their overweight or obese, there will be no effect on weight at first and second line treatments when they consumed. It is just that doctors have to discuss medications and their potential effects on weight with patients.
For treating the obesity in patients with type 2 diabetes, it helps in recommending certain medications including angiotensin-converting enzyme inhibitors, angiotensin receptor, and calcium channel blockers must have to be used in the treatment for the first-line treatment for high blood pressure. There are also other alternative medications such as beta-adrenaergic blockers as they are also very effective in treating blood pressure that less likely to contribute to weight gain drugs. Avoid using Phentermine in patients with uncontrolled high blood pressure or a history of heart disease or drug abuse.